Howdy!

At the heart of our research is a deep commitment to advancing our understanding of the biological and functional processes that underlie cognitive aging. Our work centers on the mechanisms that contribute to age-related cognitive impairment, with an emphasis on how circadian rhythm disruption affects brain function in the aging population. Our mission is to advance understanding of the mechanisms behind age-related cognitive impairment and uncover potential therapeutic strategies.

Welcome to the Souza Lab!

60x magnification of the dentate gyrus–hippocampal region in mice treated with Staph (staphylococcus infection). Microglia appear clustered, with orange regions indicating colocalization of DAPI, IBA-1, and CD68 staining.

60x Magnification of the dentate gyrus - hippocampal region in mice given placebo (PBS). Microglia exhibit no activation (absence of orange overlap) and display resting morphology.

Images of multiple actograms, which visualizes the periodic activity of mice during different light-dark cycles.

60x magnification of the dentate gyrus–hippocampal region in mice treated with Staph (staphylococcus infection). Microglia appear clustered, with orange regions indicating colocalization of DAPI, IBA-1, and CD68 staining.

1/7